Some of the compounds that doctors most frequently use in this form of treatment include psilocybin mushrooms, LSD, and mescaline (peyote). The formal study of psychedelics to treat mental health conditions is relatively new, but emerging research suggests that these psychedelics may help some people with visit this site some symptoms, especially when other methods of treatment have failed. Psychedelic therapy focused on psilocybin has garnered much new interest lately as a potential treatment against anxiety, depression and other mental ills. Larger studies have primarily asked current users about their experiences. One tapped more than a thousand microdosers who reported increased energy, better work results, and more positive moods. Another compared 4,000 microdosers to a similar group of nonusers and found that among people with prior mental-health issues, those who microdosed reported having lower levels of anxiety and depression.